| Issue |
Photoniques
Number 131, 2025
Quantum Sensing
|
|
|---|---|---|
| Page(s) | 58 - 61 | |
| Section | Focus: quantum sensing | |
| DOI | https://doi.org/10.1051/photon/202513158 | |
| Published online | 16 May 2025 | |
(Quantum) Fisher Information in Localization Microscopy
1
University of Vienna, Faculty of Physics, VCQ, A-1090 Vienna, Austria
2
University of Vienna, Max Perutz Laboratories, Department of Structural and Computational Biology, A-1030 Vienna, Austria
3
Naturwissenschaftlich-Technische Fakultät, Universität Siegen, Siegen 57068, Germany
4
Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-Biocenter 1, Vienna 1030, Austria
5
Biomedical Imaging Group, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland
* thomas.juffmann@univie.ac.at
The precise localization of particles yields structural and dynamical information in applications ranging from fundamental physics to molecular biology. Here, we discuss how the concept of (Quantum) Fisher information can guide the development of localization techniques. Starting from dipole scattering, we discuss imaging based on elastic and inelastic (e.g. fluorescence) scattering and present experimental designs that increase the information obtained per detected photon.
© EDP Sciences, 2025
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